Rabbit Human C1q Antibody

CAT: 0013-GTR17700595Size: 1 mLDry Ice: NoHazardous: No

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CAT#:0013-GTR17700595Size:1 mL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Precipitating polyclonal rabbit antiserum to the C1q subunit of C1 component of human complement. C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s. C1q has a molecular weight of 492.000 and is present in plasma in an average concentration of 80 mg/ml. It consists of a complex of 18 polypeptide chains of three different types, A, B and C; 6 of each type. The subcomponent C1q is responsible for the binding of C1q to immunocomplexes an membranes via the Fc portion of the immunoglobulin. The subunit C1q is isolated as a homogenous protein for use in antiserum production. Freund's complete adjuvant is used in the first step of the immunization procedure.

UniProt

P02746

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Source

C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s. C1q has a molecular weight of 492.000 and is present in plasma in an average concentration of 80 μg/ml. It consists of a complex of 18 polypeptide chains of three different types, A, B and C; 6 of each type. The subcomponent C1q is responsible for the binding of C1q to immunocomplexes an membranes via the Fc portion of the immunoglobulin. The subunit C1q is isolated as a homogenous protein for use in antiserum production. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Field of Research

Immunology & Inflammation

Form

Delipidated, heat inactivated lyophilized stable whole antiserum. No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum. No foreign proteins added.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Host or Source

Rabbit

UniProtKB · P02746

Complement C1q subcomponent subunit B

C1QB_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P02746
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: C1QB
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: Q5T959, Q96H17

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Domain

CollagenRepeatSignal

Biological process

Complement pathwayImmunityInnate immunity

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationPyrrolidone carboxylic acid

Cellular component

Secreted

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