Products for Research Use Only

MPD2

CAT: 0013-GTR19262506-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262506-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPD2 is a PROTAC compound based on a Cereblon-binding ligand that degrades the main protease MPro of SARS-CoV-2. In 293T cells, it effectively reduces MPro protein levels with a DC50 of 296 nM and shows time-dependent activity. MPD2 exhibits strong antiviral properties against various SARS-CoV-2 strains and has increased potency against Nirmatrelvir-resistant variants. It holds potential for researching SARS-CoV-2 diseases.
Field of Research
Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Molecular Formula
C51H68N6O13
Storage Conditions
-20°C
Notes
For research use only.

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