N-Propargylglycine

CAT: 0804-HY-142035-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-142035-01Size:5 mg

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Description

N-Propargylglycine is an orally active irreversible inhibitor of proline dehydrogenase (PRODH) . N-Propargylglycine has antitumor activity and can be used in the study of neurodegenerative diseases[1].

CAS Number

58160-95-5

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-propargylglycine.html

Purity

99.70

Solubility

DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O)CNCC#C

Molecular Formula

C5H7NO2

Molecular Weight

113.11

Precautions

H315, H319

References & Citations

[1]Scott GK, et al. N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties. Amino Acids. 2021 Dec;53 (12) :1927-1939.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature, keep dry and cool

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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