Products for Research Use Only
RegisterLogin

Rabbit Human fibonectin Antibody

CAT: 0013-GTR17700586Size: 1 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR17700586Size:1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Precipitating polyclonal rabbit antiserum to human fibronectin. Fibronectin is a glycoprotein with a molecular weight of 440,000 and consists of two identical peptide chains. Its mean concentration in plasma is 330 mg/ml. Elevated plasma levels of fibronectin are observed in chronic active liver disease; decreased values are found in cases of acute leukaemia, sepsis, severe burns, acute pancreatitis, inflammatory processes, haemorrhagic shock and polytrauma. Fibronectin is also present on cell surfaces. It cab be cross-linked to the fibrin clot by the action of F XIIIA. As formation of the clot occurs approximately 50% of the plasma Fibronectin is lost. Freund's complete adjuvant is used in the first step of the immunization procedure.
UniProt
P02751
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Fibrinogen (clotting factor I) is a heat labile beta glycoprotein (molecular weight 340,000) and consists of three pairs of chains bound by disulphide bonds. It is synthesized in hepatocytes under genetic control. It is the precursor of fibrin, which is the key protein constituting the network of the blood clot. Thrombin converts fibrinogen to fibrin by limited proteolysis, releasing the fibrinopeptides A and B (molecular weight 50,000-65,000) and forming fibrin monomers. Fibrin monomers polymerize to fibrin which is stabilized by cross-linking under the influence of factor XIII. The predominant gamma chain of normal fibrinogen (MW 50,000, with higher variants) has a low affinity for platelet binding. Fibrinogen is isolated from fresh plasma after removing prothrombin. Freund’s complete adjuvant is used in the first step of the immunization procedure.
Form
Delipidated, heat inactivated, lyophilized, stable whole antiserum. Sodium azide 0.7 mg/ml Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled rabbit serum. No foreign proteins added.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Host or Source
Rabbit

Related Products

CatalogName
GTR18307765Fibronectin Rabbit Polyclonal Antibody
GTR18400268-01Fibronectin Rabbit monoclonal antibody
GTR18400681-01Fibronectin Rabbit monoclonal antibody
GTR18721580-01Fibronectin Rabbit Monoclonal Antibody
GTR18678264-01Fibronectin Rabbit Polyclonal Antibody
GTR18230842-01Fibronectin Rabbit Polyclonal Antibody
GTR18232771-01Fibronectin Rabbit Polyclonal Antibody
GTR18111314-01Fibronectin Rabbit Polyclonal Antibody
GTR17695860Fibronectin Rabbit Monoclonal Antibody
GTR18520643-01Fibronectin Rabbit Polyclonal Antibody

Alternative Products

CatalogName
MBS573354-01Rabbit anti Human fibonectin
M0012Human, Rabbit PINCH antibody
M0001Human, Rabbit AKT2 antibody
M0008Human, Rabbit MAP2K2 antibody
M0011Human, Rabbit PHB1 antibody
M0003Human, Rabbit BRAF antibody
M0007Human, Rabbit LSD1 antibody
M0006Human, Rabbit GSK3B antibody
M0005Human, Rabbit DDX4 antibody
M0004Human, Rabbit CHK2 antibody

Popular Products