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DS96432529

CAT: 0804-HY-145121-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145121-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DS96432529 is a potent and orally active bone anabolic agent through CDK8 inhibition.
CAS Number
2871872-79-4
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ds96432529.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(N)C2=C(N3C[C@@H](COCCOCC)CCC3)C=CN=C2S1)N
Molecular Formula
C18H26N4O3S
Molecular Weight
378.49
References & Citations
[1]Saito K, et al. Discovery of 3-amino-4-{ (3S) -3-[ (2-ethoxyethoxy) methyl]piperidin-1-yl}thieno[2,3-b]pyridine-2-carboxamide (DS96432529) : A potent and orally active bone anabolic agent. Bioorg Med Chem Lett. 2021 Dec 15;54:128440.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK8

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