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PAN endonuclease-IN-2

CAT: 0013-GTR19262139-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262139-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAN endonuclease-IN-2 (compound T-31) is a PAN endonuclease inhibitor (IC50: 0.15 μM) and has antiviral properties with broad-spectrum anti-influenza activity. PAN, as the N-terminal PA subunit of the polymerase-RNA complex, possesses a cap-dependent endonuclease (CEN) active site, facilitating RNA cleavage and initiating the synthesis of new RNA molecules. PAN endonuclease-IN-2 targets both influenza HA and RdRp complexes, thereby disrupting viral entry into host cells and impeding viral replication.
Field of Research
Infectious Disease & Virology
Molecular Formula
C25H21Br2NO7
Storage Conditions
-20°C
Notes
For research use only.

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