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II399

CAT: 0013-GTR19261800-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261800-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
II399 is a potent and selective dual-substrate inhibitor of NNMT, featuring an unconventional SAM mimic, with a Ki value of 5.9 nM. It exhibits a notable competitive inhibition pattern against NAM and can occupy both the substrate and cofactor binding pockets. II399 shows promise for research in cancer, metabolic, cardiovascular, and neurodegenerative diseases.
CAS Number
2928480-72-0
Smiles
O[C@H]1[C@H] (N2C=3C (C=C2) =C (Cl) N=CN3) C[C@H] (CN (CC#CC4=CC (C (N) =O) =CC=C4) C (C) =O) [C@H]1O
Molecular Formula
C24H24ClN5O4
Molecular Weight
481.93
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T209161-01II399

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