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Minoxidil

CAT: 0804-HY-B0112-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0112-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3].
CAS Number
38304-91-5
Product Name Alternative
U10858
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Minoxidil.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 7.14 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 50°C)
Smiles
NC1=NC(N2CCCCC2)=CC(N)=[N+]1[O-]
Molecular Formula
C9H15N5O
Molecular Weight
209.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Hadjipavlou-Litina D, et al. Synthesis and evaluation of the antioxidative potential of minoxidil-polyamine conjugates. Biochimie. 2013 Jul;95 (7) :1437-49. doi: 10.1016/j.biochi.2013.03.009. Epub 2013 Mar 28.|[2]Davies GC, et al. Novel and established potassium channel openers stimulate hair growth in vitro: implications for their modes of action in hair follicles. J Invest Dermatol. 2005 Apr;124 (4) :686-94.|[3]Cohen RL, et al. Direct effects of minoxidil on epidermal cells in culture. J Invest Dermatol. 1984 Jan;82 (1) :90-3.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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CatalogName
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