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Reveromycin C

CAT: 0013-GTR19261470-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261470-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Reveromycin C is a polyketide compound originally isolated from Streptomyces, exhibiting antifungal activity against Candida albicans with a MIC of 2.0 μg/mL at pH 3 and >500 μg/mL at pH 7.4. It inhibits EGF-induced mitogenic activity in Balb/MK mouse epidermal cell lines. Additionally, it reverses the morphology of sarcoma virus-transformed NRK rat kidney cells (EC50 = 1.58 μg/mL) and inhibits the proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50 = 2.0 μg/mL for both) .
CAS Number
144860-69-5
Field of Research
Infectious Disease & Virology
Smiles
O (C (CCC (O) =O) =O) [C@@]1 (CCC (C) C) [C@H] (/C=C/C (=C/C (O) =O) /C) O[C@@]2 (CC1) O[C@H] (C/C=C (/C=C/[C@@H] ([C@H] (/C=C/C (O) =O) C) O) \C) [C@@H] (C) CC2
Molecular Formula
C37H54O11
Molecular Weight
674.82
Storage Conditions
-20°C
Notes
For research use only.

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