Products for Research Use Only

PXB17

CAT: 0013-GTR19260873-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19260873-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PXB17 inhibits CSF1R activation (IC50= 1.7 nM) by blocking the PI3K/AKT/mTORC1 signaling pathway. It is effective orally, significantly suppresses the growth of colorectal cancer (CRC), enhances the efficacy of PD-1 monoclonal antibodies (PD-1mAb), and reduces the recurrence of CRC tumors.
Field of Research
Signal Transduction
Molecular Formula
C29H35N7O4
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-158050PXB17