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Mavoglurant

CAT: 0013-GTR19260773-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19260773-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mavoglurant (AFQ056) is a potent, selective, non-competitive, and orally active metabotropic glutamate receptor 5 (mGluR5) antagonist with an IC50 of 30 nM, demonstrating greater than 300-fold selectivity over 238 tested targets, and it is widely applied in research on Fragile X syndrome and L-dopa-induced dyskinesias in Parkinson’s disease, while Mavoglurant incorporated alkyne functional group, which enables copper-catalyzed azide–alkyne cycloaddition click chemistry, facilitating target engagement and molecular tracking studies.
CAS Number
543906-09-8
Field of Research
Pharmacology & Drug Discovery
Purity
99.91% (May vary between batches)
Smiles
C (#CC1=CC (C) =CC=C1) [C@@]2 (O) [C@]3 ([C@] (N (C (OC) =O) CC3) (CCC2) [H]) [H]
Molecular Formula
C19H23NO3
Molecular Weight
313.39
Storage Conditions
-20°C
Notes
For research use only.

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