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Cyclomorusin

CAT: 0013-GTR19260327-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19260327-01Size:25 mg
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Description
Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM.
CAS Number
62596-34-3
Purity
>98% (HPLC)
Molecular Formula
C25H22O6
Molecular Weight
418.44
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

Cyclomorusin

Cyclomorusin A is an extended flavonoid that is cyclomulberrin in which the hydroxy group at position 10 has undergone oxidative cyclisation to position 3 of the 3-methylbut-2-en-1-yl substituent, with migration of the double bond into conjugation with the aromatic ring. It is a moderate inhibitor of acetylcholinesterase (IC50 = 16.2 - 36.6 M), and a strong inhibitor of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) induced platelet aggregation. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a platelet aggregation inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor and a plant metabolite. It is a polyphenol, an organic heteropentacyclic compound, a cyclic ketone and an extended flavonoid. It is functionally related to a cyclomulberrin.

CAS Number62596-34-3
PubChem CID5481969
IUPAC Name11,19-dihydroxy-7,7-dimethyl-15-(2-methylprop-1-enyl)-2,8,16-trioxapentacyclo[12.8.0.03,12.04,9.017,22]docosa-1(14),3(12),4(9),5,10,17(22),18,20-octaen-13-one
Molecular FormulaC25H22O6
Molecular Weight418.4
XLogP5.2
Topological Polar Surface Area85.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Heavy Atom Count31
Formal Charge0
Complexity850
SMILES
CC(=CC1C2=C(C3=C(O1)C=C(C=C3)O)OC4=C(C2=O)C(=CC5=C4C=CC(O5)(C)C)O)C
InChI
InChI=1S/C25H22O6/c1-12(2)9-19-21-22(28)20-16(27)11-18-15(7-8-25(3,4)31-18)23(20)30-24(21)14-6-5-13(26)10-17(14)29-19/h5-11,19,26-27H,1-4H3
InChIKey
GDQXJMLXEYSICD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cyclomorusin
CAS: 62596-34-3
CID: 5481969
Formula: C25H22O6
MW: 418.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight418.4
XLogP35.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Exact Mass418.14163842
Monoisotopic Mass418.14163842
Topological Polar Surface Area85.2 Ų
Heavy Atom Count31
Formal Charge0
Complexity850
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M38892-01Cyclomorusin

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