Products for Research Use Only

ODN 2216 sodium

CAT: 0013-GTR19264825-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264825-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ODN 2216 sodium is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. It induces significant production of IFN-α and IFN-β. The compound stimulates IFN-α through pDC (plasmacytoid dendritic cells) and produces IL-12 (p40) via DC (dendritic cells) . ODN 2216 triggers peripheral blood mononuclear cells (PBMC) to produce IFN-γ indirectly, mediated by IFN-α/β. Additionally, ODN 2216 sodium can activate NK cells and enhance IFN-γ production in TCR-triggered CD4+ T cells.
Field of Research
Cell Biology, Immunology & Inflammation
Storage Conditions
-20°C
Notes
For research use only.