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LYA914

CAT: 0013-GTR19264728-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264728-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LYA914 is an orally active AR/AR-V7 PROTAC degrader. It targets the proteolysis of the androgen receptor's (AR) conserved DNA-binding domain (DBD) . LYA914 demonstrates effective antiproliferative activity in Enzalutamide-insensitive or resistant cells and inhibits tumor growth in VCaP/LNCaP tumor mouse models. It is suitable for studying castration-resistant prostate cancer (CRPC) .
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-175455LYA914

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