Products for Research Use Only

(GalNAc) 3-CPT

CAT: 0013-GTR19264693-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264693-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(GalNAc) 3-CPT is a glycan-conjugated prodrug that targets the asialoglycoprotein receptor (ASGR) overexpressed on liver cells. It demonstrates significant antitumor activity by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumor sites, leading to apoptosis of tumor cells. In HepG2 cells, it shows an IC50 value of 3.07 μM.
Field of Research
Cell Biology, Metabolism Research
Storage Conditions
-20°C
Notes
For research use only.