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PRMT7-IN-2

CAT: 0013-GTR19263228-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263228-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PRMT7-IN-2 (A33) is a selective inhibitor of PRMT7 with an IC50 value of 0.50 μM. It causes cell cycle arrest at the G0/G1 phase, induces apoptosis, and inhibits cell growth both in vivo and in vitro. PRMT7-IN-2 reduces monomethylation levels of arginine by PRMT7, increases the expression of the epithelial marker E-cadherin, and decreases the expression of mesenchymal markers N-cadherin, Vimentin, and ZEB2.
CAS Number
3058094-83-7
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
N1=C (N=C (NC=2C=CC=3N=C (C=C (N) C3C2) C) C=4SC=CC14) C5=CC (OC) =C (OC) C (OC) =C5
Molecular Formula
C25H23N5O3S
Molecular Weight
473.55
Storage Conditions
-20°C
Notes
For research use only.

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