Products for Research Use Only

WRN inhibitor 10

CAT: 0013-GTR19262969-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262969-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WRN inhibitor 10 (Compound P24) is an inhibitor of the Werner helicase WRN, with an IC50 of 1.1 nM. It effectively inhibits the proliferation of SW48 cancer cells, with an IC50 of 39 nM. WRN inhibitor 10 exhibits favorable liver microsomal stability and membrane permeability, and demonstrates good pharmacokinetic properties in CD-1 mice.
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Molecular Formula
C31H29BrClN9O5S
Storage Conditions
-20°C
Notes
For research use only.