Products for Research Use Only

SL44

CAT: 0013-GTR19262809-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262809-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SL44 is an agonist of human caseinolytic protease P (HsClpP) with an EC50 of 1.30 μM. It inhibits LM3 proliferation with an IC50 of 3.1 μM and induces apoptosis in liver cancer cells by degrading respiratory chain complex subunits. In mouse models, SL44 demonstrates antitumor activity without significant toxicity (LD50=400 mg/kg) and exhibits favorable pharmacokinetic properties in rat models.
Field of Research
Protein Biochemistry
Molecular Formula
C22H20ClFN4O
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-162650-01SL44