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AGB1

CAT: 0013-GTR19261216-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261216-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AGB1 is a highly selective and potent B&H-PROTAC degrader. It degrades Ab:Brd4BD2 L387A and Ab:BromoTag-Brd2 with pDC50 values of 7.8 and 7.9, respectively. AGB1 has an affinity for VHL with a Kd of 125 nM. In mice, AGB1 exhibits favorable pharmacokinetic properties [DC50, 6 h approximately 13 nM].
Field of Research
Pharmacology & Drug Discovery
Molecular Formula
C51H63ClN8O9S2
Storage Conditions
-20°C
Notes
For research use only.

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