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3-sucCA

CAT: 0013-GTR19259621-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259621-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3-Succinylated cholic acid (3-sucCA) is a microbially derived bile acid that plays a significant role in gut health and metabolic regulation. As a lumen-restricted metabolite, 3-sucCA has been shown to mitigate the progression of metabolic-associated fatty liver disease (MAFLD) to metabolic-associated steatohepatitis (MASH) in mouse models. Its protective effects are primarily attributed to its ability to reshape the gut microbiota, particularly by enhancing the growth of Akkermansia muciniphila, a beneficial bacterium associated with improved metabolic health. Notably, patients with biopsy-confirmed MAFLD exhibit reduced levels of 3-sucCA, underscoring its potential as a biomarker and therapeutic target for managing metabolic liver diseases. This unique metabolite highlights the intricate interplay between gut microbiota and liver health, offering promising avenues for intervention.
CAS Number
94159-47-4
Purity
>98%
Smiles
CC (CCC (=O) O) C1CCC2C1 (C (CC3C2C (CC4C3 (CCC (C4) OC (=O) CCC (=O) O) C) O) O) C
Molecular Formula
C28H44O8
Molecular Weight
508.644169807434
Notes
For research use only.

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