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AC3573

CAT: 0013-GTR19259527Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259527Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AC3573 (AC-3573) is a potent, specific small molecule inhibitor of HER3.AC3573 abrogates HER2–HER3 signalling in cells and is more specific for HER3, inhibits NRG (heregulin) -induced HER3 phosphorylation with IC50 of 10 uM, abrogates the formation of the active HER2-HER3 heterodimer, inhibits oncogenic downstream signalling in SK-BR-3 breast cancer cells.
Purity
>98%
Molecular Formula
C18H15N5O2S
Molecular Weight
365.411
Notes
For research use only.

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