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X396

CAT: 0013-GTR19259481-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259481-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ensartinib, also known as X-396, is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.
CAS Number
1370651-20-9
Purity
>98%
Smiles
C1 (C (NC2=CC=C (C (N3C[C@H] (C) N[C@H] (C) C3) =O) C=C2) =O) =NN=C (N) C (O[C@@H] (C2=C (Cl) C=CC (F) =C2Cl) C) =C1
Molecular Formula
C26H27CL2FN6O3
Molecular Weight
561.435386896133
Notes
For research use only.

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