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Antiparasitic agent-26

CAT: 0013-GTR19258696-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258696-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage) . It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM) .
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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