DGAT1-IN-1

DGAT1-IN-1

• CAS Number: 1449779-49-0
• UNSPSC Description: DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1). IC50 value: < 10 nM Target: DGAT1 inhibitor Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation By Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.
• Target Antigen: Acyltransferase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/DGAT1-IN-1.html
• Purity: 98.0
• Solubility: DMSO : 20 mg/mL (ultrasonic)
• Smiles: OC(C[C@H]1CC[C@H](C2=CC=C(C3=CN4C=C(C(NCC5=CC=C(OC(F)(F)F)C=C5)=O)N=C4C=C3)C=C2)CC1)=O
• Molecular Weight: 551.56
• References & Citations: [1]Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme&#x0D; , Patent: WO 2013119040 A1
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported