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PLK1-IN-13

CAT: 0013-GTR19258466-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258466-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLK1-IN-13 is a selective, orally active PLK1 inhibitor with an IC50 of 0.27 nM. It also inhibits PLK2 (IC50: 12.72 nM) and PLK3 (IC50: 4.12 nM) . PLK1-IN-13 induces cell cycle arrest at the G2 phase, promotes apoptosis, and downregulates the transcription of the cancer-associated oncogene c-MYC. This compound inhibits tumor growth and is applicable for research in acute myeloid leukemia (AML) .
CAS Number
3038489-48-1
Field of Research
Cell Biology, Signal Transduction
Smiles
C (C) [C@H]1N (C=2C (N (C) C1=O) =CN=C (NC3=C (OC) C=C (C=C3) C=4SC (CN5CCN (C) CC5) =NN4) N2) C6CCCC6
Molecular Formula
C29H39N9O2S
Molecular Weight
577.744
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
HY-173212PLK1-IN-13
527088-01PLK1
040171PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13)
MBS6334971-01PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (AP)
MBS6334974-01PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (FITC)
MBS6334981-01PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (PE)
MBS6334973-01PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (Biotin)
MBS6334972-01PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (APC)
MBS6334978-01PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (MaxLight 550)
040171-APCPLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (APC) discontinued

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