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PSB-24000

CAT: 0013-GTR19258318-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258318-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for inhibiting human CD73, and a Ki of 481 nM in membrane-bound CD73 in triple-negative breast cancer cells. It disrupts CD73’s recognition and action on substrate AMP, preventing AMP-induced immunosuppressive and pro-cancer adenosine production. PSB-24000 is promising for cancer research.
Field of Research
Immunology & Inflammation
Storage Conditions
-20°C
Notes
For research use only.

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