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VU0467319

CAT: 0013-GTR19258206-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258206-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU0467319 (Compound VU319) is a highly selective positive allosteric modulator of the M1 receptor, capable of crossing the blood-brain barrier and orally active, with an EC50 of 492 nM. It demonstrates selectivity in humans and rats (EC50 > 30 μM) compared to M2-5 receptors. This compound improves cognitive deficits associated with Alzheimer's disease (AD) through central M1 muscarinic receptor activation and does not induce cholinergic adverse effects, highlighting its potential in AD research.
CAS Number
1432438-14-6
Field of Research
Neuroscience
Smiles
O=C1C2=CC=CN=C2CN1CC=3C (F) =CC (=CC3F) C4=CC=CC5=NN (C=C54) C
Molecular Formula
C22H16F2N4O
Molecular Weight
390.385
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T206889-01VU0467319

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