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H052

CAT: 0013-GTR19258048-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258048-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla) . It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.
CAS Number
2886748-00-9
Field of Research
Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C1NC=2C=C (C (=CC2NC1=O) S (=O) (=O) NC3=CC=C (C (Cl) =C3) C=4C=CC (F) =CC4) C
Molecular Formula
C21H15ClFN3O4S
Molecular Weight
459.88
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T207113-01H052

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