Products for Research Use Only

P53 Stabilizer 2

CAT: 0013-GTR19257850-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257850-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P53 Stabilizer 2 (Compound 17a16) is a p53 stabilizing agent. It can induce S-phase arrest and apoptosis in both p53-functional and p53-deficient cancer cells. Additionally, p53 Stabilizer 2 triggers mitochondrial stress and activates two immune checkpoint pathways: NA-PKcs dependent p53 stabilization and the ATR-Chk1 axis activation. It also inhibits tumor growth in p53-deficient xenograft models.
CAS Number
2531685-87-5
Field of Research
Cancer Biology, Cell Biology
Smiles
O (C) C=1C=2[C@@] (N (C) CCC2C (C[Se]C3CCCCCC3) =C4C1OCO4) ([C@@]5 (C=6C (C (=O) O5) =C (OC) C (OC) =CC6) [H]) [H]
Molecular Formula
C30H37NO7Se
Molecular Weight
602.58
Storage Conditions
-20°C
Notes
For research use only.