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MS105

CAT: 0013-GTR19257836-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257836-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MS105 is an orally active, selective protein tyrosine kinase 6 (PTK6) PROTAC degrader. It recruits the VHL E3 ligase through a VHL ligand fragment, facilitating ubiquitination and proteasomal degradation of PTK6, thereby inhibiting the proliferation and migration of breast cancer cells and inducing apoptosis (apoptosis) . MS105 is a promising compound for breast cancer research.
CAS Number
2408339-39-7
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
N (C=1C=2N (C (=CN2) C=3C=NNC3) C=C (N1) C4CC4) C5=C (F) C=C (C (=O) N6CCN (CC (NCCCCCCCCC (N[C@H] (C (=O) N7[C@H] (C (NCC8=CC=C (C=C8) C=9SC=NC9C) =O) C[C@@H] (O) C7) [C@] (C) (C) C) =O) =O) CC6) C=C5
Molecular Formula
C56H70FN13O6S
Molecular Weight
1072.30
Storage Conditions
-20°C
Notes
For research use only.

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