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Nav1.2-IN-1

CAT: 0013-GTR19257823-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257823-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nav1.2-IN-1 (compound 5i) is a 3- (1,2,3,6-tetrahydropyridine) -4-azaindole derivative that acts as a potent and selective Nav1.2 inhibitor. It effectively reduces the peak current of Nav1.2 with an IC50 of 7.79 μM. Nav1.2-IN-1 demonstrates antiepileptic activity and shows strong anticonvulsant effects with low neurotoxicity in a subcutaneous pentylenetetrazol (sc-PTZ) induced seizure model.
CAS Number
3084825-09-9
Field of Research
Pharmacology & Drug Discovery
Molecular Formula
C20H18F3N3
Storage Conditions
-20°C
Notes
For research use only.

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