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SM875

CAT: 0013-GTR19257553-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257553-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SM875 is a degrader specifically targeting the cellular prion protein (PrP) with an IC50 of 7.87 μM. By binding to the folding intermediates of PrP, SM875 facilitates their degradation via the autophagy-lysosome pathway. It acts exclusively on nascent, immature PrP molecules and does not affect mature PrP synthesized beforehand. SM875 has the potential to inhibit prion replication, making it a promising compound for research in neurodegenerative diseases, particularly prion diseases.
CAS Number
919023-94-2
Smiles
O=C1NC2=C (C=NN2C3=CC=C (Br) C=C3) C (C4=CC=C (O) C (OC) =C4) C1
Molecular Formula
C19H16BrN3O3
Molecular Weight
414.25
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-150286-01SM875
HY-150286A(R) -SM875

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