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3-O-methyl Estradiol

CAT: 0013-GTR19257979-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257979-01Size:50 mg
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Description
3-O-methyl Estradiol is a synthetic estrogen known for its ability to interfere with microtubule networks in V79 Chinese hamster cells, with an EC50 value of 9 μM. At a concentration of 20 μM, it inhibits the proliferation of these cells by 92%. Additionally, when male rats on a high-cholesterol diet are administered 3-O-methyl Estradiol (25 mg in a 0.2 ml solution, p.o.), it results in decreased serum cholesterol levels and increases body weight loss, suggesting feminizing effects. It has also been utilized as a standard for quantifying 17β-estradiol in hen urine.
CAS Number
1035-77-4
Field of Research
Pharmacology & Drug Discovery
Smiles
C[C@@]12[C@] ([C@]3 ([C@@] (C=4C (CC3) =CC (OC) =CC4) (CC1) [H]) [H]) (CC[C@@H]2O) [H]
Molecular Formula
C19H26O2
Molecular Weight
286.41
Storage Conditions
-20°C
Notes
For research use only.

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