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SB334867 HCl

CAT: 0013-GTR19257492-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257492-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB-334867 (SB 334867A) is a potent, selective, and blood-brain barrier permeable antagonist of the orexin-1 (OX1) receptor, demonstrating significant selectivity against OX2 (pKb=7.4), and exhibiting 100-fold selectivity over 5-HT2B and 5-HT2C, with pKi values of 5.4 and 5.3, respectively. This compound effectively reduces ethanol consumption and obstructs the development of morphine-induced sensitization to locomotor activity in vivo.
CAS Number
249889-64-3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
Cl.Cc1nc2ccc (NC (=O) Nc3ccnc4cccnc34) cc2o1
Molecular Formula
C17H14ClN5O2
Molecular Weight
355.78
Storage Conditions
-20°C
Notes
For research use only.

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