Products for Research Use Only

KIF18A-IN-6

CAT: 0013-GTR19257295-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257295-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor that suppresses KIF18A microtubule-dependent ATPase activity with an IC50 of 0.016 μM. It reduces HCC15 tumour volume in mouse models and may be employed in KIF18A-associated cancer research.
CAS Number
2914879-10-8
Field of Research
Signal Transduction
Purity
97.59% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (5.9 mM) ; DMSO:100 mg/mL (178.65 mM)
Smiles
O=C (C1=CC=CC (=C1) S (=O) (=O) NC (C) (C) C) N2C3=CC=C (C=C3C4 (C2) CCC5 (CC4) CC5) NS (=O) (=O) CC
Molecular Formula
C28H37N3O5S2
Molecular Weight
559.74
Storage Conditions
-20°C
Notes
For research use only.