TMPD (dihydrochloride)

TMPD (dihydrochloride)

• CAS Number: 637-01-4
• UNSPSC Description: TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases[1][2]. TMPD dihydrochloride is also a complex IV substrate[3].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/tmpd-dihydrochloride.html
• Purity: 98.83
• Solubility: DMSO : 16.67 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
• Smiles: CN(C)C1=CC=C(N(C)C)C=C1.[H]Cl.[H]Cl
• Molecular Weight: 237.17
• References & Citations: [1]S Kuss, et al. Electrochemical recognition and quantification of cytochrome c expression in Bacillus subtilis and aerobe/anaerobe Escherichia coli using N, N, N', N'-tetramethyl- para-phenylene-diamine (TMPD). Chem Sci. 2017 Nov 1;8(11):7682-7688.|[2]Nenad Petrovic, et al. Using N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) to assay cyclooxygenase activity in vitro. Methods Mol Biol. 2010;594:129-40.|[3]Franco A Rossato, et al. Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration. PLoS One. 2014 Jun 25;9(6):e101060.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: Phase 3