Products for Research Use Only
RegisterLogin

Senecionine

CAT: 0804-HY-N2560-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N2560-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) [1][2][3].
CAS Number
130-01-8
Product Name Alternative
Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin
UNSPSC
12352005
Hazard Statement
H300+H310+H330
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Senecionine.html
Purity
99.48
Solubility
DMSO : 1.43 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1O[C@@]2([H])[C@]3([H])N(CC=C3COC([C@](C)(O)[C@H](C)C/C1=C/C)=O)CC2
Molecular Formula
C18H25NO5
Molecular Weight
335.39
Precautions
H300+H310+H330
References & Citations
[1]Wang C, et al. The comparative pharmacokinetics of two pyrrolizidine alkaloids, senecionine and adonifoline, and their main metabolites in rats after intravenous and oral administration by UPLC/ESIMS. Anal Bioanal Chem. 2011 Jul;401 (1) :275-87.|[2]Kakrani HK, et al. Effect of seneciphylline and senecionine on hepatic drug metabolizing enzymes in rats. J Ethnopharmacol. 1984 Dec;12 (3) :271-8.|[3]Tu ZB, et al. Identification of senecionine and senecionine N-oxide as antifertility constituents in Senecio vulgaris. J Pharm Sci. 1988 May;77 (5) :461-3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
TBW00147Senecionine
466023-01Senecionine-D3
MBS5817583Senecionine acetate
TBW00153Senecionine-N-Oxide
CS-T-61177Senecionine N-Oxide
RM-S110001-01Senecionine Impurity 1

Popular Products