Gilvusmycin

CAT: 0013-GTR19255689-02Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19255689-02Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Gilvusmycin is an antibiotic with potent antitumor properties. It effectively inhibits the proliferation of P388, K562, A431, and MKN28 cells, with IC50 values (ng/mL) of 0.08, 0.86, 0.72, and 0.75, respectively.

CAS Number

195052-09-6

Field of Research

Infectious Disease & Virology

Smiles

C (=O) (N1C=2C3 (C (C3) C1) C4=C (C (=O) C2) NC=C4C) C5=CC6=C (N5) C (OC) =C (O) C7=C6CCN7C (=O) C8=CC9=C (N8) C (OC) =C (O) C%10=C9CCN%10C (C) =O

Molecular Formula

C38H34N6O8

Molecular Weight

702.712

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Gilvusmycin

Gilvusmycin is an antibiotic isolated from the culture broth of Streptomyces sp. QM16 with potent cytotoxic activity against the human tumor cells. It has a role as a metabolite, an antimicrobial agent and an antineoplastic agent. It is a member of phenols, an aromatic ether, a bridged compound, an organonitrogen heterocyclic compound and a cyclic ketone.

CAS Number	195052-09-6
PubChem CID	9810316
IUPAC Name	10-[6-(6-acetyl-5-hydroxy-4-methoxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carbonyl)-5-hydroxy-4-methoxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carbonyl]-3-methyl-5,10-diazatetracyclo[7.4.0.01,12.02,6]trideca-2(6),3,8-trien-7-one
Molecular Formula	C38H34N6O8
Molecular Weight	702.7
XLogP	3
Topological Polar Surface Area	184
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Heavy Atom Count	52
Formal Charge	0
Complexity	1610

SMILES

CC1=CNC2=C1C34CC3CN(C4=CC2=O)C(=O)C5=CC6=C7CCN(C7=C(C(=C6N5)OC)O)C(=O)C8=CC9=C1CCN(C1=C(C(=C9N8)OC)O)C(=O)C

InChI

InChI=1S/C38H34N6O8/c1-15-13-39-29-24(46)11-25-38(26(15)29)12-17(38)14-44(25)37(50)23-10-21-19-6-8-43(31(19)33(48)35(52-4)28(21)41-23)36(49)22-9-20-18-5-7-42(16(2)45)30(18)32(47)34(51-3)27(20)40-22/h9-11,13,17,39-41,47-48H,5-8,12,14H2,1-4H3

InChIKey

XUBJLJZOSKJNMY-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 195052-09-6

CID: 9810316

Formula: C38H34N6O8

MW: 702.7

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	702.7
XLogP3	3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	702.24381206
Monoisotopic Mass	702.24381206
Topological Polar Surface Area	184 Å²
Heavy Atom Count	52
Formal Charge	0
Complexity	1610
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
HY-N14523	Gilvusmycin

Gilvusmycin

Chemical Information

Alternative Products

Popular Products