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Oximidine III

CAT: 0013-GTR19255541-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19255541-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oximidine III is an antitumor antibiotic that selectively inhibits the growth of rat fibroblast 3Y1 cells and induces mutations in various tumor genes. The inhibitory effects of Oximidine III on vH-ras-3Y1, v-src-3Y1 cells, and normal 3Y1 cells have IC50 values of 14 nM, 4.5 nM, and 140 nM, respectively. Additionally, Oximidine III arrests cells with RAS or SRC mutations in the G1 phase of the cell cycle and increases the expression of p21WAF1.
CAS Number
664365-72-4
Field of Research
Infectious Disease & Virology
Smiles
C (/C=C/NC (/C=C\C=N\OC) =O) [C@H]1C[C@]2 ([C@] (O2) (/C=C\C=C\C=3C (C (=O) O1) =C (O) C=CC3) [H]) [H]
Molecular Formula
C23H24N2O6
Molecular Weight
424.45
Storage Conditions
-20°C
Notes
For research use only.

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