Products for Research Use Only
RegisterLogin

Cipepofol

CAT: 0804-HY-116152-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-116152-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol. Cipepofol can activate the sirtuin1 (Sirt1) /Nrf2 pathway. Cipepofol protects the heart against Isoproterenol (ISO; HY-B0468) -induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis[1][2].
CAS Number
1637741-58-2
Product Name Alternative
Ciprofol; HSK3486
UNSPSC
12352005
Target
Apoptosis; GABA Receptor; Keap1-Nrf2; Sirtuin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Membrane Transporter/Ion Channel; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/cipepofol.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC=CC([C@@H](C2CC2)C)=C1O)C
Molecular Formula
C14H20O
Molecular Weight
204.31
References & Citations
[1]Ming Lu, et al. Ciprofol: A Novel Alternative to Propofol in Clinical Intravenous Anesthesia? Biomed Res Int. 2023 Jan 19:2023:7443226.|[2]Yunzhao Yang, et al. Ciprofol attenuates the isoproterenol-induced oxidative damage, inflammatory response and cardiomyocyte apoptosis. Front Pharmacol. 2022 Nov 22:13:1037151.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
BA2931-25Cipepofol
TYD-03663-01Cipepofol glucuronide
GTR19266999-01(S) -Cipepofol

Popular Products