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Pronqodine A

CAT: 0013-GTR19255249-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19255249-01Size:50 mg
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Description
Pronqodine A is a quinone isolated from Streptomyces, known for its enzyme inhibitory and anti-inflammatory properties. It targets NAD (P) H:quinone acceptor oxidoreductase 1 (NQO1; IC50 = 131.5 nM) . In SW 982 human synovial sarcoma cells, it suppresses bradykinin-induced production of prostaglandin E2 (PGE2), 6-keto PGF1α, and PGD2, with IC50 values of 9, 19, and 7 nM, respectively, and it also promotes the generation of reactive oxygen species (ROS) in these cells.
CAS Number
1424195-39-0
Field of Research
Immunology & Inflammation, Metabolism Research
Smiles
O=C1C=C (NC) C (=O) C=2C=NSC12
Molecular Formula
C8H6N2O2S
Molecular Weight
194.21
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-N16372Pronqodine A

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