Products for Research Use Only

MS2133

CAT: 0013-GTR19257595-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257595-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MS2133 is a DOT1L PROTAC degrader. It facilitates the ubiquitination and degradation of DOT1L in THP-1 and MV4-11 cells, with DC50 values of 56 nM and 25 nM, respectively, and reduces H3K79 methylation. MS2133 also inhibits the growth of MLL-r leukemia cells, demonstrating anticancer activity.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C58H66ClF3N14O11S2
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T207647-01MS2133