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Raxatrigine

CAT: 0804-HY-12796-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12796-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Raxatrigine (GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.
CAS Number
934240-30-9
Product Name Alternative
Vixotrigine; GSK-1014802; CNV1014802
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/CNV1014802.html
Purity
99.85
Solubility
DMSO : 83 mg/mL (ultrasonic; warming)
Smiles
O=C([C@H]1N[C@@H](C2=CC=C(OCC3=CC=CC=C3F)C=C2)CC1)N
Molecular Formula
C18H19FN2O2
Molecular Weight
314.35
Precautions
H302, H315, H320, H335
References & Citations
[1]Large CH, et al. The efficacy of sodium channel blockers to prevent phencyclidine-induced cognitive dysfunction in the rat: potential for novel treatments for schizophrenia. J Pharmacol Exp Ther. 2011 Jul;338 (1) :100-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Nav1.7

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A21645-5Raxatrigine hydrochloride 5mg
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