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Tegafur (Standard)

CAT: 0804-HY-17400R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17400R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tegafur (Standard) is the analytical standard of Tegafur. This product is intended for research and analytical applications. Tegafur (FT 207; NSC 148958) is a chemotherapeutic 5-FU proagent used in the treatment of cancers; is a component of tegafur-uracil.
CAS Number
17902-23-7
Product Name Alternative
FT 207 (Standard) ; NSC 148958 (Standard)
UNSPSC
12352005
Hazard Statement
H301-H311-H331
Target
Nucleoside Antimetabolite/Analog; Reference Standards
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tegafur-standard.html
Smiles
O=C1NC(C(F)=CN1C2OCCC2)=O
Molecular Formula
C8H9FN2O3
Molecular Weight
200.17
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
[1]Sotaro Sadahiro, Toshiyuki Suzuki, Akira Tanaka, et al. Association of right-sided tumors with high thymidine phosphorylase gene expression levels and the response to oral uracil and tegafur/leucovorin chemotherapy among patients with colorectal cancer. Cancer Chemotherapy and Pharmacology. 2012, 70 (2) : 285-291.|[2]José L. Ariasa, et al. Engineering of an antitumor (core/shell) magnetic nanoformulation based on the chemotherapy agent ftorafur. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2011,384 (1-3) : 157-163.|[3]Gabriel N. Hortobagyi, William Heim, Laura Hutchins, et al. A phase 2 study of a fixed combination of uracil and ftorafur (UFT) and leucovorin given orally in a 3-times-daily regimen to treat patients with recurrent metastatic breast cancer. Cancer. 2010, 116 (6) : 1440-1445.|[4]K. Fujita, H. Nakayama, W. Ichikawa, et al. Pharmacokinetics of 5-Fluorouracil in Elderly Japanese Patients with Cancer Treated with S-1 (a Combination of Tegafur and Dihydropyrimidine Dehydrogenase Inhibitor 5-Chloro-2,4-dihydroxypyridine) . Drug Metab Dispos. 2009 Jul;37 (7) :1375-7. doi: 10.1124/dmd.109.027052. Epub 2009 Apr 23.|[5]Tegafur-uracil
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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