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EGFR-IN-140

CAT: 0013-GTR19250413-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250413-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-140 (Compound 31) is a potent, small-molecule EGFR inhibitor effective against wild-type and resistant mutants, including EGFRL858R/T790M/C797S. It demonstrates nanomolar activity in biochemical and cellular assays (e.g., Ba/F3 cells) and has shown in vivo antitumor efficacy in mouse models, supporting its use in oncology research targeting EGFR-driven cancers.
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CCC1=CN2C (=CC (=N2) NC3=NC (=NC=C3) N4CC[C@H] ([C@H] (C4) F) OC) N1C5CCC6 (CC5) CCN (C6=O) C
Molecular Formula
C27H37FN8O2
Molecular Weight
524.633
Storage Conditions
-20°C
Notes
For research use only.

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