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DBAZ2

CAT: 0013-GTR19250011-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250011-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DBAZ2 is a first-in-class PROTAC degrader specifically targeting the BAZ2A and BAZ2B bromodomain proteins, demonstrating potent degradation with DC50 values of 180 nM and 250 nM, respectively. This tool compound enables the investigation of BAZ2A/B function in epigenetic regulation and cancer biology, supporting both in vitro and in vivo mechanistic studies.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC1=C (SC=N1) C2=CC=C (C=C2) CNC (=O) [C@@H]3C[C@H] (CN3C (=O) C (C (C) (C) SCC4CCC (CC4) COCC5=NC (=C (N5CCC6=CN (N=C6) C) C7=CC=C (C=C7) C#N) C8=CN (N=C8) C) NC (=O) C9 (CC9) F) O
Molecular Formula
C54H64FN11O5S2
Molecular Weight
1030.29
Storage Conditions
-20°C
Notes
For research use only.

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