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HLB-0532259

CAT: 0013-GTR19249908-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249908-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HLB-0532259 is a bifunctional PROTAC molecule that induces the degradation of Aurora-A and N-Myc proteins, demonstrating DC50 values in the nanomolar range across various cell lines. It has shown promising antitumor efficacy in preclinical mouse models, supporting its application in cancer research, particularly for studying MYCN-amplified cancers and targeted protein degradation.
CAS Number
2566733-45-5
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
O=C (NCCCCCCOC1=CC=CC=2C (=O) N (C (=O) C12) C3C (=O) NC (=O) CC3) C4=CC=C (C=C4) NC=5N=CC=6C=C (C (=O) N (C) C) N (C6N5) C7CCCC7
Molecular Formula
C40H44N8O7
Molecular Weight
748.827
Storage Conditions
-20°C
Notes
For research use only.

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