Products for Research Use Only
RegisterLogin

CQ627

CAT: 0013-GTR19249732-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19249732-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CQ627 is a molecular glue degrader that recruits E3 ligase RNF126 to ubiquitinate and degrade RIOK2 via the proteasome (DC50 = 410 nM in MOLT4 cells) . It demonstrates dose-dependent apoptosis, G2/M phase arrest, and broad antiproliferative activity in cancer cell lines, with confirmed efficacy in MOLT4 xenograft models.
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
COC1=NC=C (C=C1) C2=CC3=C (C=C2) NC (=O) C4=C3N (N=N4) C5=CC (=C (C=C5) N6CCN (CC6) C (=O) /C=C/C (=O) C7=CC=C (C=C7) F) C (F) (F) F
Molecular Formula
C36H27F4N7O4
Molecular Weight
697.638
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T204921-01CQ627

Popular Products