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EGFR-IN-141

CAT: 0013-GTR19249690-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249690-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-141 (Compound 8I) is a potent EGFR inhibitor (IC50 = 2.67 nM) demonstrating cytotoxic activity in A549 cells (IC50 = 13.75 μM) . It induces apoptosis and mitochondrial membrane depolarization, supporting its investigation as a potential antitumor agent in cancer research, including studies of non-small cell lung carcinoma (NSCLC) mechanisms.
CAS Number
3054263-27-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C1C=2C=CC=CC2N=CN1CC3=NN=C (SCC (=O) NC4=NC=5C=CC (F) =CC5S4) N3N
Molecular Formula
C20H15FN8O2S2
Molecular Weight
482.514
Storage Conditions
-20°C
Notes
For research use only.

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