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Pyrimidinone 8

CAT: 0013-GTR19249622-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249622-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pyrimidinone 8 is a reversible, linear non-competitive inhibitor of human DMT1 (Ki=20 μM) that blocks cellular iron uptake (IC50=13.8 μM) without altering transporter surface expression or pH sensitivity. This tool compound is useful for in vitro studies of iron metabolism and metal transporter biology.
CAS Number
65004-42-4
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1N=C (NC (=C1) C) N2N=C (C=C2C) C
Molecular Formula
C10H12N4O
Molecular Weight
204.229
Storage Conditions
-20°C
Notes
For research use only.

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